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... Kollarcíková Miloslava - llleal and caecal microbiota of chickens - identification of new opportunistic pathogens ... ... Brno, CZ) -- 12:00- 12.25am Plzakova Lenka - Early cellular responses of germ free and specific pathogen ... ... break - Congress foyer -- 10:30- 10:55am Prokšová Magdaléna - Seeking host target of Francisella pathogenicity ...
54 nečíslovaných stran : barevné ilustrace ; 22 cm
- MeSH
- interakce hostitele a parazita MeSH
- Publikační typ
- abstrakty MeSH
- kongresy MeSH
- programy MeSH
- souborné dílo MeSH
- zprávy MeSH
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- infekční lékařství
Journal of clinical investigation. 12, ISSN 0021-9738 Supplement Vol. 100
S69 s. : il. ; 30 cm
V referáte sú zhrnuté novšie poznatky o Aeromonas species z hľadiska ich taxonómie, ekológie, epidemiológie, klinického významu a potenciálnych faktorov virulencie.
The authors summarized the newer data on Aeromonas species from the point of view of the taxonomy, ecology, epidemiology, clinical significance as well as of potential factors of virulence.
The 14th Host-Pathogen Interaction Forum was held in Kutná Hora, Czech Republic, between November 7 - 10, 2022. The Forum was traditionally organized by the Faculty of Military Health Sciences, Hradec Králové, Czech Republic, in collaboration with the Czech Immunological Society in Prague, Czech Republic.
- MeSH
- interakce hostitele a patogenu * MeSH
- kongresy jako téma * MeSH
- Publikační typ
- zprávy MeSH
Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. Traditionally, tick-borne pathogen detection has been carried out using PCR-based methods that rely in known sequences for specific primers design. This approach matches with the view of a 'single-pathogen' epidemiology. Recent results, however, have stressed the importance of coinfections in pathogen ecology and evolution with impact in pathogen transmission and disease severity. New approaches, including high-throughput technologies, were then used to detect multiple pathogens, but they all need a priori information on the pathogens to search. Thus, those approaches are biased, limited and conceal the complexity of pathogen ecology. Currently, next generation sequencing (NGS) is applied to tick-borne pathogen detection as well as to study the interactions between pathogenic and non-pathogenic microorganisms associated to ticks, the pathobiome. The use of NGS technologies have surfaced two major points: (i) ticks are associated to complex microbial communities and (ii) the relation between pathogens and microbiota is bidirectional. Notably, a new challenge emerges from NGS experiments, data analysis. Discovering associations among a high number of microorganisms is not trivial and therefore most current NGS studies report lists of microorganisms without further insights. An alternative to this is the combination of NGS with analytical tools such as network analysis to unravel the structure of microbial communities associated to ticks in different ecosystems.
- MeSH
- Bacteria izolace a purifikace MeSH
- interakce hostitele a patogenu MeSH
- klíšťata mikrobiologie MeSH
- koinfekce mikrobiologie MeSH
- lidé MeSH
- mikrobiální interakce MeSH
- mikrobiota * MeSH
- nemoci přenášené klíšťaty diagnóza mikrobiologie MeSH
- vysoce účinné nukleotidové sekvenování MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
The host-pathogen interaction represents a complex and dynamic biological system. The outcome of this interaction is dependent on the microbial pathogen properties to establish infection and the ability of the host to control infection. Although bacterial pathogens have evolved a variety of strategies to subvert host defense functions, several general mechanisms have been shown to be shared among these pathogens. As a result, host effectors that are critical for pathogen entry, survival and replication inside the host cells have become a new paradigm for antimicrobial targeting. This review focuses on the potential utility of a proteomics approach in defining the host-pathogen interaction from the host's perspective.
The crayfish plague pathogen, Aphanomyces astaci Schikora, has become one of the most well-studied pathogens of invertebrates. Since its introduction to Europe in the mid-19th century, it has caused mass crayfish mortalities, resulting in drastic declines of local populations. In contrast, North American crayfish usually serve as latent carriers, although they may also be negatively affected by A. astaci infections under some circumstances. Recent research benefiting from molecular tools has improved our knowledge about various aspects of A. astaci biology. In this review, we summarize these advances, particularly with respect to the host range and transmission. We highlight several aspects that have recently received particular attention, in particular newly confirmed or suspected A. astaci hosts, latent A. astaci infections in populations of European crayfish, and the relationship between A. astaci genotype groups and host taxa.
- MeSH
- Aphanomyces genetika fyziologie MeSH
- interakce hostitele a patogenu * MeSH
- severní raci mikrobiologie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Geografické názvy
- Evropa MeSH