• Keywords
• zemřelý dárce orgánů,
• MeSH
• Tissue and Organ Harvesting ethics   methods   standards   instrumentation   utilization   legislation & jurisprudence   MeSH

• Keywords
• Extrakorporální membránová oxygenace, Ex-vivo perfúze,
• MeSH
• Biomedical Research methods   trends   MeSH
• Pulmonary Surgical Procedures methods   trends   utilization   MeSH
• Humans MeSH
• Extracorporeal Circulation methods   utilization   MeSH
• Tissue and Organ Harvesting methods   trends   utilization   MeSH
• Lung Diseases * etiology   complications   therapy   MeSH
• Respiratory Insufficiency * surgery   therapy   MeSH
• Statistics as Topic MeSH
• Lung Transplantation * methods   trends   utilization   MeSH
• Tissue and Organ Procurement methods   trends   utilization   MeSH
• Check Tag
• Humans MeSH
• Geographicals
• Czech Republic MeSH
• Canada MeSH
• Austria MeSH
• United Kingdom MeSH

• Keywords
• MRCP - (magnetická rezonanční cholangiografie a pankreatografie), ERCP - (endoskopická retrográdní cholangiopankreatografie = cholangiopankreatikografie), CT a 3D CT cholangiografie, "Mother-baby" cholangioskopie, SpyGlass, Intraduktální sonografie, Přímá transpapilární cholangioskopie, Perkutánní transhepatální cholangioskopie,
• MeSH
• Choledocholithiasis therapy   MeSH
• Diagnostic Techniques, Digestive System * instrumentation   trends   utilization   MeSH
• Endosonography methods   trends   utilization   MeSH
• Humans MeSH
• Bile Duct Diseases * diagnosis   prevention & control   therapy   MeSH
• Tissue and Organ Harvesting methods   instrumentation   utilization   MeSH
• Statistics as Topic MeSH
• Constriction, Pathologic prevention & control   therapy   MeSH
• Ultrasonography * methods   trends   utilization   MeSH
• Check Tag
• Humans MeSH

České právní normy definují dva druhy odběrů orgánů od zemřelých dárců. Jsou jimi dárci s prokázanou smrtí mozku (DBD – donors after brain death) a dárci po nevratné zástavě krevního oběhu (DCD – donors after circulatory death). Zatímco první typ dárcovství je v České republice běžnou součástí klinické praxe, dárcovství orgánů po nevratné zástavě oběhu je teprve na samotném počátku. V druhé polovině roku 2013 byl schválen kompetentními odbornými společnostmi doporučený postup k provádění těchto odběrů. V uvedené kazuistice 45letého muže po závažném úrazu mozku se snažíme upozornit na některé odlišnosti a případná rizika DCD.

Two separate types of organ donation from dead donors exist in the Czech law. The first type is donation from donors after brain death (DBD) and the second type is donation from donors after cardiac death (DCD). While the first type is a routine part of clinical practice in the Czech Republic, donation from donors after circulatory death is in its begin-nings. The recommendation of competent professional societies for donation after cardiac death was approved in 2013. In this case report of a 45-year old man after severe brain injury, we try to point out the important differences in the cardiac (circulatory) death donation proces.

• MeSH
• Conscious Sedation MeSH
• Intensive Care Units MeSH
• Middle Aged MeSH
• Humans MeSH
• Brain Death diagnosis   physiopathology   MeSH
• Tissue and Organ Harvesting * ethics   standards   utilization   MeSH
• Brain Injuries * diagnosis   physiopathology   therapy   MeSH
• Cause of Death MeSH
• Radionuclide Imaging MeSH
• Family MeSH
• Practice Guidelines as Topic MeSH
• Heart Arrest MeSH
• Organ Transplantation MeSH
• Tissue and Organ Procurement * ethics   standards   utilization   MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Publication type
• Case Reports MeSH

Článek přináší kazuistiku pacientky přijaté po resuscitaci v mimonemocničním prostředí a popisuje průběh od přijetí, přes stanovení infaustní prognózy až po přechod na paliativní péči, stanovení smrti a odběr orgánů za účelem transplantace. Jedná se o první publikaci odběru od tzv. kontrolovaného dárce zemřelého v důsledku nevratné zástavy oběhu v České republice. Detailně je popsán praktický průběh přípravy na odběr, popis přechodu na paliativní péči zahrnující odpojení pacientky od ventilátoru, i přínos echokardiografie v diagnostice zástavy oběhu. Článek je ilustrativním příkladem typického průběhu odběru orgánů od dárce kategorie Maastricht 3. Je představen protokol použitý pro diagnózu ireverzibilní zástavy oběhu a jsou rovněž zmíněny základní právní a etické aspekty odběru od této skupiny dárců.

This case study reports the initial management, prognosis assessment and withdrawal of life support followed by retrieval of vital organs for transplantation in a patient admitted after out-of-hospital cardiac arrest. This is the first description of a case of controlled donation after circulatory death in the Czech Republic. We discuss in detail the practical aspects of organ retrieval management, the role of echocardiography in circulatory arrest, indication of palliative treatment including terminal weaning and determining death due to circulatory arrest. We also emphasize communication with family members. The protocol used to determine death after circulatory arrest is presented along with the basic ethical and legal considerations in this sub-group of organ donors.

• MeSH
• Conscious Sedation MeSH
• Adult MeSH
• Echocardiography MeSH
• Intensive Care Units MeSH
• Kidney MeSH
• Humans MeSH
• Hypoxia, Brain etiology   physiopathology   MeSH
• Brain Death diagnosis   legislation & jurisprudence   MeSH
• Tissue and Organ Harvesting * ethics   standards   utilization   standards   utilization   legislation & jurisprudence   MeSH
• Palliative Care MeSH
• Cause of Death MeSH
• Family MeSH
• Practice Guidelines as Topic MeSH
• Heart Arrest * diagnosis   physiopathology   therapy   MeSH
• Kidney Transplantation MeSH
• Transplantation legislation & jurisprudence   MeSH
• Medical Futility MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Female MeSH
• Publication type
• Case Reports MeSH
• Review MeSH

• MeSH
• Staining and Labeling methods   utilization   MeSH
• Tissue Fixation methods   utilization   MeSH
• Immunohistochemistry methods   utilization   MeSH
• Humans MeSH
• Spinal Cord pathology   MeSH
• Brain pathology   MeSH
• Neurodegenerative Diseases * diagnosis   pathology   MeSH
• Neuropathology * methods   organization & administration   trends   MeSH
• Tissue and Organ Harvesting methods   utilization   MeSH
• Autopsy * methods   utilization   MeSH
• Statistics as Topic MeSH
• Check Tag
• Humans MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH
• Geographicals
• Czech Republic MeSH

• Keywords
• dárcovství orgánů, právní a etické aspekty dárcovství,
• MeSH
• Tissue Donors ethics   MeSH
• Humans MeSH
• Tissue and Organ Harvesting * ethics   utilization   legislation & jurisprudence   MeSH
• Surveys and Questionnaires utilization   MeSH
• Registries standards   MeSH
• Statistics as Topic MeSH
• Transplantation ethics   legislation & jurisprudence   MeSH
• Public Opinion * MeSH
• Living Donors psychology   MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Female MeSH
• Geographicals
• Slovakia MeSH

Aim/objective Prospective study comparing objective and subjective parameters of patients undergoing myocardial revascularization surgery. Venous graft were harvested by both endoscopic and the bridging method. Methodology In the period from 01/2009 to 03/2010, we performed 45 combined harvests of v. saphena magna using the endoscopic and bridging method. Patients went through an ambulatory control of wound complications after one week and after one month. Another inspection was carried out by telephone after three months when the patients completed a short questionnaire. After one year, details of major adverse cardiac and cerebrovascular events (MACCE) were collected. The agreement of patients was obtained prior to their participation in this study. Results The average age of patients was 66.3 years (55–84), the average BMI was 28.9 (24.1–36.6) and in the observed group men predominated (77.8%). Diabetes was present in 24.4%, varicose of lower extremities in 20% and peripheral arterial occlusive disease in 11.1% of patients. The average length of harvested vein, the velocity of harvest and the number of sutured defects per vein were quite similar. Early complications occurred in a total of 5 patients (11.1%), after completion of the endoscopic harvest in 1 patient (2.2%) and after the bridging harvest in 4 patients (8.9%). In the questionnaire completed three months after the surgery patients mentioned less pain, better cosmetic results and greater overall satisfaction in the endoscopic harvest (75.6% of patients). If patients had had the choice, in most cases (88.9%) they would have preferred the endoscopic harvest to the bridging technique harvest. For the vast majority of respondents (93.3%) a scar on the chest and a scar on the lower extremities after harvesting of vein grafts are equal from a cosmetic point of view. Major adverse cardiac and cerebrovascular events (MACCE) were reported over one year in 8.9% of patients. Conclusions Comparing the two minimally invasive techniques (endoscopic and bridging) in the selected group of patients we have demonstrated a lower incidence of wound complications and greater patient satisfaction with endoscopic harvesting methods. Both of these minimally invasive methods are safe for the patients, which were demonstrated by low occurrence of MACCE.

• Keywords
• ranné komplikace,
• MeSH
• Lower Extremity surgery   MeSH
• Endoscopy methods   utilization   MeSH
• Cardiovascular Surgical Procedures methods   utilization   MeSH
• Humans MeSH
• Minimally Invasive Surgical Procedures methods   utilization   MeSH
• Tissue and Organ Harvesting classification   methods   utilization   MeSH
• Postoperative Complications prevention & control   MeSH
• Prospective Studies MeSH
• Surveys and Questionnaires MeSH
• Myocardial Revascularization methods   utilization   MeSH
• Patient Satisfaction MeSH
• Statistics as Topic MeSH
• Transplants utilization   MeSH
• Saphenous Vein transplantation   MeSH
• Outcome and Process Assessment, Health Care MeSH
• Check Tag
• Humans MeSH

• MeSH
• Chemotherapy, Adjuvant utilization   MeSH
• Biological Therapy utilization   MeSH
• Chromogranin A analysis   diagnostic use   MeSH
• Phosphopyruvate Hydratase analysis   diagnostic use   drug effects   MeSH
• Carcinoembryonic Antigen analysis   blood   MeSH
• Keratin-19 analysis   diagnostic use   MeSH
• Humans MeSH
• Biomarkers, Tumor analysis   MeSH
• Lung Neoplasms diagnosis   drug therapy   therapy   MeSH
• Tissue and Organ Harvesting methods   utilization   MeSH
• Gastrin-Releasing Peptide analysis   diagnostic use   MeSH
• Mass Screening methods   trends   utilization   MeSH
• Predictive Value of Tests MeSH
• Serum MeSH
• Tissue Polypeptide Antigen analysis   MeSH
• Transcription Factors analysis   diagnostic use   MeSH
• Check Tag
• Humans MeSH

• MeSH
• Reproductive Techniques, Assisted utilization   MeSH
• Fertilization in Vitro MeSH
• Infertility epidemiology   physiopathology   MeSH
• Cryopreservation MeSH
• Humans MeSH
• Pregnancy, Ectopic etiology   prevention & control   MeSH
• Infertility, Male diagnosis   etiology   therapy   MeSH
• Tissue and Organ Harvesting methods   utilization   MeSH
• Insemination, Artificial MeSH
• Infertility, Female diagnosis   etiology   therapy   MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Female MeSH