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The article presents results of peculiarities of the hepatobiliary system in pregnant women with preeclampsia. It is set in the pregnant with preeclampsia of mild severity the frequency and combination of two and more complaints was reliably lower comparing to the frequency and combination of complaints in the pregnant with preeclampsia of mean severity. It must be mentioned that the received laboratory data positively correlated with the clinical manifestations of hepatobiliary dysfunction and the level of severity of preeclampsia that makes the further scientific researches necessary in future. Among the ultrasound signs of the dysfunction of the hepatobiliary system the following were detected: hepatomegaly, diffuse changes in the liver, increasing the density of the gallbladder against the decrease in contractility of the formation of sludge.
Competencies develop and changes throughout a persons life, they can gain or lose, going through various age stages. Their development does not end in youth, but continue on through the adult life. The ability to thing and reflect those thoughts specifically come forward in the center of structure of competency, which grows at the same time as the individual matures. One of the competency types is health competency. Health competency is a relatively new concept; it is not sufficiently researched. Aim of the study was to determine the factors of an adult individual health competency. 827 respondents participated in the study, in the processing of data was used SPSS. Was used factor analysis, analysis of variance with ANOVA and KruskalWallis test and Pearsons correlation. It was found that health competency is affected by several factors. These are: health education, health behavior, and the value of the environment. Each of the sets was distributed to key factors. It is the main factors affecting the health competence, but additional factors are: gender, education and income.
- MeSH
- dospělí MeSH
- environmentální zdraví MeSH
- hodnotící studie jako téma MeSH
- kvalita života * MeSH
- lidé MeSH
- mladý dospělý MeSH
- péče o sebe MeSH
- postoj ke zdraví * MeSH
- sběr dat MeSH
- statistika jako téma MeSH
- zdraví MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- práce podpořená grantem MeSH
- Geografické názvy
- Lotyšsko MeSH
The author reported clinical characteristic features and risk factors for acute intestinal infections in 225 children (140 boys and 85 girls, mean age 1.5 years old). 90 (40%) patients aged up to 12 months, 101 (44.9%) were from 1 to 2 years old, and 34 (15.1%) were more than 2 years old. Most children were hospitalized in the first week of illness and had moderate severe course of disease. Severe forms of illness reliably more often were noted in children being on artificial feeding. Toxicdystrophic condition, severe forms and perinatal encephalopathy were prevailed in boys. Factorial analysis revealed 20 most significant factors with factorization fullness 70.8%. The most significant factors were F1( factor of hyperthermia duration) with 8.5% effect, F2 (factor of pain syndrome) 5.8%, F3 (factor of normal enzymatic activity of colon bacillus) 4.9%, F4 (etiological factor) 4.6%, as well as F5( factor of opportunistic flora of the intestine) 4.4%, respectively.
Performance evaluation of scientific work on regional and individual levels can be achieved by the using scientometric methods of a quantitative analysis of bibliographic information available in such databases as Science Citation Index (SCI). Unfortunately, Kazakhstan scientific journals have not been included yet in the Thomson Reuters Corp. register of periodicals, that substantially distorts the actual national scientometric indexes. The analysis of Database “National Citation Reports” (Kazakhstan), which correlated with a contribution of Kazakhstan into the world science development, has shown the low level of research activities of Kazakhstan scientists on international arena. So, the share of international publications of Kazakhstan in the global flow is equal to 0,021 % (1044 doc.) that corresponds to the 87th place in the general list of countries of 177 names. Subject to the ranking of countries into groups by the number of the published works, Kazakhstan is referring to the group of 46 countries having 1000-10000 publications over 5 years, of which 8,6% in medicine. In this article the use of statistics and appropriate software by the authors of original articles in such journals as recommended by the Kazakh National Centre for Scientific & Technical Expertise (NCSTE) and included in the Database еlibrary.kz was evaluated. Research was conducted according to Research Report, due to which a research design and statistical analysis methods were estimated. In the rating of the research design, the authors of articles mostly used as follows: description of a series of cases–63,2%, description of the individual cases -27,1%, and description of specific cases–9,1%. A scope of selection in Section “Research Methods” was only calculated in 21,8% of cases, and in 63,9% of cases there was no description how the selection was carried out. Methods of analytical statistics were used in the 46,0% of cases. And there were references to the program package in use only in 17,5% of works. Thus shown that non-compliance with international standards in the preparation of scientific papers, primarily statistical requirements directly affect the quality and ratings of domestic articles.
- MeSH
- periodika jako téma * MeSH
- publikační zkreslení MeSH
- publikování MeSH
- statistika jako téma * metody normy MeSH
- výzkumný projekt * MeSH
- Geografické názvy
- Kazachstán MeSH
Assaultive acts committed by people with a mental illness is a major public health issue that affects patients with their families, law enforcement authorities, and the public at large. Failure to provide treatment is in fact a major predictor of assaultive acts in patients with schizophrenia living in the community. Considering that the indigenous ethnic groups of Central Asia have similar sociocultural characteristics, these factors may be reflected in individuals with schizophrenia who have committed serious assaultive acts in Uzbekistan. Objectives: The aim of the work was to identify the sociocultural and clinical characteristics of schizophrenic representatives of indigenous ethnic groups of Central Asia who have committed violent crimes in Uzbekistan and have been found insane in regard to their offence, and to compare these subjects to ones belonging to the other ethnic groups. Material and methods: The data were collected in 2010–2013 in the Tashkent High Security Psychiatric Hospital via face-to-face interviews and also from the patients’ charts and from forensic psychiatric examination statements. Results: The sample consisted of 201 individuals. The sample was 90.1 percent (n = 181) male, with a predominance of the paranoid schizophrenia subtype according to the ICD-10 criteria. Of the subjects, 174 ones (86.6%) were representatives of the indigenous ethnic groups of Central Asia, and 27 ones (13.4%) were representatives of other ethnic groups. The duration of illness among the subjects belonging to the indigenous ethnic groups of Central Asia was less than in the other group; the individuals were rarely referred to psychiatric care because of the popularity of alternative medicine and the stigma attached to mental illness. A positive correlation between violence and various psychotic symptoms, such as delusions, hallucinations, and thought disorder, has also been demonstrated in this group. European Medical, Health and Pharmaceutical Journal ISSN 1804-5804 Conclusions: Sociocultural characteristics, such as delayed referral for psychiatric care because of the popularity of alternative medicine and the stigma attached to mental illness among the indigenous ethnic groups of Central Asia, frequently factor into committing serious acts of assault because of developing psychotic symptoms at the early stages of disease despite their sufficient socioenvironmental adaptation.
- MeSH
- dospělí MeSH
- etnicita psychologie MeSH
- kohortové studie MeSH
- kulturní charakteristiky * MeSH
- lidé středního věku MeSH
- lidé MeSH
- násilí * etnologie prevence a kontrola psychologie MeSH
- pacientův souhlas se zdravotní péčí psychologie MeSH
- populační charakteristiky MeSH
- psychotické poruchy etiologie MeSH
- rizikové faktory MeSH
- schizofrenie * etiologie etnologie terapie MeSH
- sociální prostředí MeSH
- statistika jako téma MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Geografické názvy
- Uzbekistán MeSH
Objective: To determine risk factors in different pathogenic subtypes of ischemic stroke in Tashkent hospital registry and to compare with the data of other stroke registers. Design: Prospective observational study. Participants: 300 adults aged 18 years or over who suffered first-ever acute ischemic stroke, of them, the data of 100 patients with atherothrombotic, lacunar and cardioembolic strokes were analyzed. Main outcome measures: Mathematically significant differences and not significant differences but interesting from other point of view. Categorical variables are expressed as frequencies and percentages. Differences were regarded as statistically significant when the P value was less than 0.05 (P<0.05). Results: Of 100 patients with acute first-ever ischemic stroke at the median age of 62.63±4.68 (interquartile range 25-92) years, 57% were men and 43% were women. Depending on aetiology and stroke subtype, all the patients were divided into three groups: 42 patients with atherothrombotic stroke, 41 – with lacunar stroke, and 17 patients with cardioembolic stroke. Atherothrombotic stroke developed often in people over 60 years old, while lacunar stroke prevailed at the younger age. Stroke cases increased in people over 51 years old. Although men were more likely to suffer strokes than women, stroke incidence was equal in both sexes with increasing of age (over 60 years old), especially in atherothrombotic stroke, testifying to that women live longer. Combination of cerebral atherosclerosis and hypertension was the most significant risk factor for stroke. Atherosclerosis was the main aetiological factor for ischemic stroke, independently of its pathogenic heterogeneity. Diabetes mellitus was an independent risk factor for all stroke subtypes, which in most cases worsened the European Medical, Health and Pharmaceutical Journal ISSN 1804-5804 course and outcome of stroke. Hypertension was the leader aetiological factor for lacunar stroke. In these patients, we Cardioembolic stroke developed mainly because of cardiac thrombosis and valve pathology, which were often associated with chronic diseases of other organs, worsening the course and outcome of stroke. Despite of high prevalence of myocardial infarction in men, women were more likely to develop cardioembolic stroke. Conclusions: This study found simultaneous influence of many risk factors (multifactorial disease) in the development of ischemic stroke. The more course and influence of the underlying disease and risk factor, the higher stroke risk and severity, especially in the absence or inadequate previous therapy of underlying disease before the stroke index. We have noted a high prevalence of under-diagnosis of vascular risk factors at levels of primary and secondary care. We recommend for improved public awareness of vascular risk factors and better diagnostic and treatment facilities aimed at addressing those factors at levels of primary and secondary healthcare. Larger population-based studies may provide additional data on stroke incidence and outcome among Uzbeks.
- MeSH
- ateroskleróza MeSH
- cévní mozková příhoda * diagnóza epidemiologie etiologie klasifikace komplikace prevence a kontrola MeSH
- dospělí MeSH
- hodnocení rizik statistika a číselné údaje MeSH
- hypertenze patologie MeSH
- komplikace diabetu MeSH
- lidé středního věku MeSH
- lidé MeSH
- pozorovací studie jako téma statistika a číselné údaje MeSH
- prospektivní studie MeSH
- rizikové faktory * MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- věkové faktory MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Geografické názvy
- Uzbekistán MeSH
The important biological role of saliva in maintaining of the homeostasis of the oral cavity environment, preventing infection and tooth decay is widely accepted. Salivary glands insufficiency may violate the balance between health and disease. Clinical data indicated that the destruction, agenesis and aplasia of salivary gland commonly followed with hypo salivation, low salivary flow, which resulted in severe caries and periodontal disease. Salivary gland dysfunction also frequently found in preterm and low birth weight newborns. But the information about structural background of abnormal salivation in early childhood is still limited. A presence of any correlation between salivary glands structural development and intrauterine restrictions of fetal growth (IUGR) is unclear. The aim of present study was to determine morphological and morphometric peculiarities of human parotid gland in case of IUGR at late gestation. Material and methods: Parotid glands of twenty human fetuses 2022 weeks of gestation with diagnosed IUGR from late abortions material were compared with ten fetal glands in cases of induced abortions due to psychological reasons (control group). Tissue samples were immersionfixed in 10% buffered formalin solution, embedded in paraffin wax. Histological slides were stained routinely with hematoxylin & eosin, with Van Gieson's Stain. Microscopical examination was performed on magnification x 40 and x 100. Stereometric study by point count method at magnification x 40 allowed finding out volume fractions (VF) of glands parenchyma and stroma. VF of lobules components (glands wall, glands lumen, ducts wall, ducts lumen, vessels, intralobular connective tissue) were registered at magnification x100. Morphometry of the secretory portion of the parotid gland was conducted on the Zeiss microscope with the help of the AxioVision Rel.4.8 program. The mature (differentiated) end pieces were measured, including their area (in mkm2), width, height, perimeter (all in mkm). Similar measurements were done in the foci of immature secretory ends of a gland. Additionally the mean height of the epithelial cells layer within the mature secretory end pieces was measured. The differences were analyzed by methods of mathematical statistics using the software Microsoft Excel; data was compared with control measurements by Students ttest. Results: The results of present research have shown the delayed differentiation of fetal parotid glands parenchymal components in case of IUGR. The parenchymal VF did not reach control values. Furthermore, VF of lobules components was also decreased. Ducts lumens appeared to be significantly narrower than at physiological gestation. Interlobular and intralobular connective tissue stroma, in contrast to the controls, occupied vast areas, and their volume fraction was increased. Deficit of the parenchymal components of the gland was enhanced by slower maturation of glands. In cases with IUGR, differentiated glands occupied smaller area, with reduced width, height and perimeter. Epithelium lining the differentiated glands is characterized by significantly lower height compared to the control group. Delayed differentiation resulted in higher proportion of immature glands. Their area, width, height and perimeter increased. IUGR was also accompanied with a variety of pathological changes. Conclusion: Present evidences suggest that IUGR leads to impaired growth and maturation of the parotid gland. Structural immaturity and lack of differentiated parenchymal elements of the organ may form the basis of its secretory functions lesion. The finding tends to support the hypothesis that the mechanism behind the increased risk of dental pathology in preterm, low birth weight and retarded children is centred at structural and functional immaturity of salivary gland.
- Klíčová slova
- stereometric study,
- MeSH
- indukovaný potrat MeSH
- lidé MeSH
- parotis * abnormality anatomie a histologie patologie růst a vývoj MeSH
- pitva MeSH
- plod * MeSH
- růstová retardace plodu * MeSH
- Check Tag
- lidé MeSH
... Klíčové otázky 24 -- 4/2 Zdroje a příklady informací při plánování projektu 24 -- 4/3 Metody sběru dat ...
Metodika ; no. 9
1. vyd. 68 s. : tab. ; 23 cm
Publikace je metodickým doporučením pro snižování rizik v prostředí hudební zábavy(diskotéky, kluby, festivaly a taneční párty), zejména s ohledem na rizika spojená s užíváním drog včetně alkoholu mezi návštěvníky. Je určena poskytovatelům preventivních a harm reduction drogových služeb, pořadatelům hudebních akcí, provozovatelům klubů a diskoték, zástupcům samospráv a voleným zástupcům. Text byl inspirován manuálem, který byl vytvořen partnery pracovní skupiny DC&D Safer Nightlife a publikován v rámci projektu Democracy, Cities & Drugs v roce 2008 pod názvem Safer Nightlife Projects: A European Proposition to Promote Safer Nightlife and Share Good Practice. Tento manuál je dostupný na stránce www.safernightlife.org/digital-library .; Tento text je metodickým doporučením pro snižování rizik v prostředí hudební zábavy (diskotéky, kluby, festivaly a taneční party), zejména s ohledem na rizika spojená s užíváním drog včetně alkoholu mezi návštěvníky. Je určen poskytovatelům preventivních a harm reduction drogových služeb, pořadatelům hudebních akcí, provozovatelům klubů a diskoték, zástupcům samospráv a voleným zástupcům.
