• MeSH
• Hepatitis diagnosis   immunology   classification   virology   MeSH
• Liver Cirrhosis diagnosis   etiology   classification   pathology   MeSH
• Liver Neoplasms diagnosis   classification   MeSH
• Liver Diseases * diagnosis   drug therapy   classification   MeSH
• Esophageal Diseases diagnosis   drug therapy   classification   MeSH
• Intestinal Diseases diagnosis   drug therapy   classification   MeSH
• Digestive System Diseases * diagnosis   drug therapy   classification   MeSH
• Biliary Tract Diseases diagnosis   drug therapy   classification   MeSH
• Publication type
• Review MeSH

• MeSH
• Surgical Wound complications   MeSH
• Embolism etiology   pathology   therapy   MeSH
• Humans MeSH
• Digestive System Diseases etiology   classification   pathology   MeSH
• Postoperative Complications * etiology   classification   therapy   MeSH
• Hemostatic Disorders etiology   classification   pathology   MeSH
• Venous Thrombosis diagnosis   etiology   therapy   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

• MeSH
• Breath Tests methods   MeSH
• Endoscopy, Digestive System instrumentation   MeSH
• Fecal Microbiota Transplantation methods   MeSH
• Helicobacter pylori pathogenicity   MeSH
• Inflammatory Bowel Diseases diagnosis   drug therapy   classification   MeSH
• Congresses as Topic MeSH
• Humans MeSH
• Pancreatic Neoplasms diagnosis   mortality   prevention & control   MeSH
• Digestive System Diseases * diagnosis   classification   prevention & control   MeSH
• Mass Screening MeSH
• Blind Loop Syndrome diagnosis   drug therapy   MeSH
• Education MeSH
• Check Tag
• Humans MeSH
• Publication type
• News MeSH

• MeSH
• Surgical Stomas classification   adverse effects   MeSH
• Defecation * MeSH
• Feces * MeSH
• Enema classification   methods   instrumentation   MeSH
• Humans MeSH
• Digestive System Diseases classification   pathology   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

• Keywords
• expozičně-eliminační testy,
• MeSH
• Digestive System Abnormalities diagnostic imaging   classification   therapy   MeSH
• Milk Hypersensitivity diagnosis   etiology   MeSH
• Intestinal Atresia diagnosis   classification   MeSH
• Hepatitis, Autoimmune diagnosis   drug therapy   therapy   MeSH
• Celiac Disease diagnosis   epidemiology   classification   therapy   MeSH
• Diagnosis, Differential MeSH
• Child MeSH
• Gastroesophageal Reflux diagnosis   drug therapy   therapy   MeSH
• Inflammatory Bowel Diseases diagnosis   classification   therapy   MeSH
• Humans MeSH
• Meckel Diverticulum diagnosis   MeSH
• Megacolon diagnosis   MeSH
• Adolescent MeSH
• Digestive System Diseases * diagnostic imaging   etiology   drug therapy   classification   therapy   MeSH
• Failure to Thrive diagnosis   etiology   therapy   MeSH
• Pyloric Stenosis diagnosis   MeSH
• Constipation diagnosis   drug therapy   physiopathology   MeSH
• Check Tag
• Child MeSH
• Humans MeSH
• Adolescent MeSH
• Publication type
• Review MeSH

• MeSH
• Hepatitis B, Chronic transmission   therapy   MeSH
• Hepatitis C, Chronic diagnosis   therapy   MeSH
• Gastrointestinal Hemorrhage MeSH
• Ischemia MeSH
• Liver Cirrhosis MeSH
• Cardiac Surgical Procedures * MeSH
• Cardiovascular Diseases surgery   complications   MeSH
• Humans MeSH
• Non-alcoholic Fatty Liver Disease diagnosis   therapy   MeSH
• Liver Diseases * classification   complications   MeSH
• Digestive System Diseases classification   MeSH
• Postoperative Complications MeSH
• Digestive System * physiopathology   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

• MeSH
• Abdomen, Acute diagnosis   therapy   MeSH
• Acute Disease * classification   therapy   MeSH
• Medical History Taking MeSH
• Diagnosis, Differential MeSH
• Gastritis etiology   pathology   therapy   MeSH
• Liver Cirrhosis complications   MeSH
• Humans MeSH
• Digestive System Diseases * diagnosis   classification   pathology   therapy   MeSH
• Pancreatitis diagnosis   pathology   therapy   MeSH
• Diarrhea diagnosis   diet therapy   drug therapy   therapy   MeSH
• Jaundice classification   therapy   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

Celiac disease (CD), also known as gluten-sensitive enteropathy or celiac sprue, is defined as a chronic, multifactorial, immune-mediated condition affecting small intestine in genetically susceptible children and adults. Gluten-sensitive enteropathy is characterized by heterogeneous clinical manifestations of variable severity that can occur at any age. For patients with prompt diagnosis and correct treatment the prognosis is excellent. Therefore, CD needs a quick diagnosis in order to start the treatment. Because of the wide range of signs and symptoms, an accurate differential diagnosis is required.

• MeSH
• Celiac Disease * diagnosis   classification   MeSH
• Diagnosis, Differential MeSH
• Child MeSH
• Humans MeSH
• Digestive System Diseases diagnosis   classification   MeSH
• Check Tag
• Child MeSH
• Humans MeSH

• MeSH
• Autoantibodies classification   MeSH
• Diagnosis, Differential MeSH
• Fibroblasts MeSH
• Humans MeSH
• Digestive System Diseases etiology   classification   therapy   MeSH
• Prognosis MeSH
• Scleroderma, Systemic * diagnosis   classification   complications   physiopathology   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

The aim of the study was to assess serum hyaluronic acid (HA) and transforming growth factor beta 1 (TGF-β1) concentrations: 1) to differentiate hepatic fibrosis from other forms of liver disease, and 2) for the non-invasive staging of canine liver fibrosis. We also evaluated the association between serum HA concentration and the size of the shunt vessel as an indirect marker of decreased liver clearance in patients with single congenital vascular anomaly. Forty-one healthy client-owned dogs and forty dogs diagnosed with hepatobiliary disease were enrolled in the prospective study. Patients were divided into 4 subgroups: 1) congenital portosystemic shunts (CPSS); 2) parenchymal diseases (a. mild and moderate fibrosis, b. advanced fibrosis and cirrhosis); 3) hepatic neoplasia; 4) biliary tract disorders based on thorough clinical, ultrasound and histopathological examination. Serum HA and TGF-β1 concentrations were measured using ELISA. The HA concentration was significantly increased in patients with advanced liver fibrosis/cirrhosis (P < 0.001) and CPSS (P < 0.001) compared to healthy dogs. Using a cut-off HA concentration of 135.94 ng/ml, the sensitivity and specificity for diagnosis for advanced liver fibrosis/cirrhosis was 100% (95% CI, 50.6–100) and 90.8% (95% CI, 81.6–95.7), respectively. The TGF-β1 levels did not significantly differ among groups (P = 0.180). Negligible correlation was found between serum HA concentration and the size of portosystemic shunt vessel (rs = 0.07; P = 0.831). These findings suggest that serum HA concentration is a potential non-invasive biomarker for advanced liver fibrosis and/or cirrhosis in dogs. The utility of measuring serum concentration of TGF-β1 for diagnosing canine liver fibrosis was not supported.

• MeSH
• Biomarkers blood   MeSH
• Biopsy methods   MeSH
• Hepatitis, Chronic blood   veterinary   MeSH
• Diagnosis, Differential MeSH
• Enzyme-Linked Immunosorbent Assay MeSH
• Liver Cirrhosis diagnosis   blood   veterinary   MeSH
• Hyaluronic Acid * blood   MeSH
• Laparoscopy methods   MeSH
• Liver Diseases diagnosis   classification   blood   veterinary   MeSH
• Digestive System Diseases diagnosis   classification   blood   veterinary   MeSH
• Prospective Studies MeSH
• Dogs MeSH
• ROC Curve MeSH
• Sensitivity and Specificity MeSH
• Statistics as Topic MeSH
• Transforming Growth Factor beta1 * blood   MeSH
• Check Tag
• Dogs MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH