Syndrom charakterizovaný necitlivostí pro bolest, ačkoli je zachovaná schopnost rozlišit škodlivé podněty od neškodných. Může být přidružena absence korneálního reflexu a mentální retardace. Jsou popsané familiární formy s autozomálně recesivní a autozomálně dominantní dědičností.

A syndrome characterized by indifference to PAIN despite the ability to distinguish noxious from non-noxious stimuli. Absent corneal reflexes and INTELLECTUAL DISABILITY may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343)

Anotace

congenital insensitivity to pain with anhidrosis = HSAN TYPE IV see NEUROPATHIES, HEREDITARY SENSORY AND AUTONOMIC

DUI

D000699 MeSH Prohlížeč

CUI

M0001066

Historická pozn.

96; was ANALGESIA, CONGENITAL 1964-95 (Prov 1964-72); PAIN INSENSITIVITY, CONGENITAL was see ANALGESIA, CONGENITAL 1973-95

Online pozn.

use PAIN INSENSITIVITY, CONGENITAL to search ANALGESIA, CONGENITAL 1966-95 (as Prov 1966-72)

Veřejná pozn.

96; was ANALGESIA, CONGENITAL 1973-95; PAIN INSENSITIVITY, CONGENITAL was see ANALGESIA, CONGENITAL 1973-95